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Title Evaluation of the Safety Profile of the ASFV Vaccine Candidate ASFV-G-?I177L
Author Xuan Hanh Tran, Le Thi Thu Phuong, Nguyen Quang Huy, Do Thanh Thuy, Van Dung Nguyen, Pham Hào Quang, Quách Võ Ngôn, Ayushi Rai, Cyril G. Gay, Douglas Paul Gladue, and Manuel Victor Borca
Date 2022-03-19
Description No commercial vaccine is currently available, although recombinant live attenuated vaccine candidates have been shown to be efficacious. In addition to determining efficacy, it is paramount to evaluate the safety profile of a live attenuated vaccine. The presence of residual virulence and the possibility of reversion to virulence are two of the concerns that must be evaluated in the development of live attenuated vaccines.
Keywords ASFV; I177L; African swine fever; ASF; vaccine; swine; reversion to virulence
URL https://www.mdpi.com/1999-4915/14/5/896
Photograph 1
ID 8136